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Franco, R. A., Martínez, J. W., Castellanos, J. M. C., Toquica, A. A. R., Medina, D. S. M., Hernández, J. P. O., Duque, J. A. S., Urrea, J. D. S., Muñoz, M. A. M., & Muñoz, V. A. G. (2015). Falla cardíaca avanzada en pacientes tratados con dispositivos electrofisiológicos en una unidad de electrofisología, Pereira (Colombia). Revista Investigaciones Andina, 16(28), 978-988. https://doi.org/10.33132/01248146.76
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Resumen
Resumen: la falla cardíaca avanzada es una enfermedad prevalente, con una tasa alta de mortalidad y hospitalización con relación a su estadio y perfil clínico, que cuesta en Norteamérica hasta el 20% de los recursos destinados para el manejo de la enfermedad cardiovascular. Se realizó un análisis transversal a una cohorte de 70 pacientes en tratamiento farmacológico y cardioresincronizador con o sin cardiodesfibirlador, o solo cardiodesfibrilador automático (ICD) implantado entre los años 2010 y 2012.
Métodos: el presente es un estudio transversal.
Resultados: 71% presentaron hipertensión arterial HTA; 65,75% cardiopatía isquémica, siendo el 58.3% portadores de resincronizador con o sin cardiodesfibrilador. El 90% de los pacientes tiene 2 o más medicamentos, 77% betabloqueador, 90% iECA o ARA II, 85.7% algún diurético.
Conclusión: se caracterizaron los pacientes que recibieron terapia electrofisiológica para manejo avanzado de falla cardíaca.
ardíaca.Palabras clave:
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Citas
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2. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. European heart journal. 2012;33(14):1787-847.
3. Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, et al. Heart Disease and Stroke Statistics—2009 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119(3):480-6.
4. Cowie MR, Mosterd A, Wood DA, Deckers JW, Poole-Wilson PA, Sutton GC, et al. The epidemiology of heart failure. European heart journal. 1997 Feb;18(2):208-25. PubMed PMID: 9043837.
5. DANE. Análisis de situación de salud según regiones Colombia. In: social Mdsyp, editor. 2013.
6. DANE. Estadísticas vitales 2013. Available from: http://www.dane.gov.co/index.php/poblacion- y-demografia/nacimientos- -defunciones.
7. Swedberg K, Cleland J, Dargie H, Drexler H, Follath F, Komajda M, et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005) The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. European heart journal. 2005;26(11):1115-40.
8. Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, Boriani G, Breithardt O-A, et al. 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy The Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA). European heart journal. 2013;34(29):2281-329.
9. Exner DV, Birnie DH, Moe G, Thibault B, Philippon F, Healey JS, et al. Canadian Cardiovascular Society Guidelines on the Use of Cardiac Resynchronization Therapy: Evidence and Patient Selection. Canadian Journal of Cardiology. 2013;29(2):182-95.
10. Keegan R, Vanegas D. Guías, Recomendaciones y Niveles de Evidencia Relacionados con La Estimulación Cardiaca y la Electrofisiología Cardiovascular 2011:26
11. Daubert JC, Saxon L, Adamson PB, Auricchio A, Berger RD, Beshai JF, et al. 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management. Heart Rhythm. 2012 Sep;9(9):1524-76. PubMed PMID: 22939223. Epub 2012/09/04. eng.
12. Hernández Madrid A, Escobar Cervantes C, Blanco Tirado B, Marín Marín I, Moya Mur JL, Moro C. Resincronización cardíaca en la insuficiencia cardíaca: bases, métodos, indicaciones y resultados. Revista Española de Cardiología. 2004;57(07):680-93.
13. Callejo D, Martín Cuerra M, Blasco JA. Terapia de resincronización cardiaca. Evaluación económica. Plan de calidad para el Sistema Nacional de Salud del Ministerio de Sanidad y Política Social. Informes de evaluación de Tecnología sanitaria UETS. Agencia Laín Entralgo, 2010.
14. 2008 Quality and Outcomes Abstracts. Circulation. 2008 May 27, 2008;117(21):e409-e68.
15. Mirowski M, Reid PR, Mower MM, Watkins L, Gott VL, Schauble JF, et al. Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings. The New England journal of medicine. 1980 Aug 7;303(6):322-4. PubMed PMID: 6991948. Epub 1980/08/07. eng.
16. Linde C, Leclercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, et al. Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study. Journal of the American College of Cardiology. 2002 Jul 3;40(1):111-8. PubMed PMID: 12103264. Epub 2002/07/10. eng.
17. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization in chronic heart failure. New England Journal of Medicine. 2002;346(24):1845-53.
18. Lemos Júnior HPd, Atallah ÁN. Cardiac resynchronization therapy in patients with heart failure: systematic review. Sao Paulo Medical Journal. 2009;127(1):40-5.
19. Callejo D, Guerra M, Hernández-Madrid A, Blasco JA. Evaluación económica de la terapia de resincronización cardiaca. Revista española de cardiología. 2010;63(11):1235-43.
20. Coma Samartín R, Sancho-Tello de Carranza MJ, Ruiz Mateas F, Leal del Ojo González J, Fidalgo Andrés ML. Registro Español de Marcapasos. VIII Informe Oficial de la Sección de Estimulación Cardiaca de la Sociedad Española de Cardiología (2010). Revista Española de Cardiología. 2011;64(12):1154-67.
21. Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC, Committee ASA, et al. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database. Journal of the American College of Cardiology. 2006 Jan 3;47(1):76-84. PubMed PMID: 16386668.
22. Actualizacion del Plan Obligatorio de Salud en Colombia, 005121 (2013).
23. Wolpert C, Lubinski A, Bissinger A, Merkely B, Priori S, Brugada J. Barriers to implementation of evidence-based electrical therapies and the need for outcome research: role of European registries. Europace. 2011;13(suppl 2):ii18- ii20.
24. Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. JAMA : the journal of the American Medical Association. 2003 May 28;289(20):2685-94. PubMed PMID: 12771115. Epub 2003/05/29. eng.
25. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. The New England journal of medicine. 2004;350(21):2140-50.
26. Beshai JF, Grimm RA, Nagueh SF, Baker JH, Beau SL, Greenberg SM, et al. Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. New England Journal of Medicine. 2007;357(24):2461-71.
27. Ruschitzka F, Abraham WT, Singh JP, Bax JJ, Borer JS, Brugada J, et al. Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex. New England Journal of Medicine. 2013;369(15):1395-405. PubMed PMID: 23998714.
28. Bansch D, Antz M, Boczor S, Volkmer M, Tebbenjohanns J, Seidl K, et al. Primary prevention of sudden cardiac death in idiopathic dilated cardiomyopathy: the Cardiomyopathy Trial (CAT). Circulation. 2002 Mar 26;105(12):1453- 8. PubMed PMID: 11914254. Epub 2002/03/27. eng.
29. Strickberger SA, Hummel JD, Bartlett TG, Frumin HI, Schuger CD, Beau SL, et al. Amiodarone versus implantable cardioverter- defibrillator:randomized trial in patients with nonischemic dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia--AMIOVIRT. Journal of the American College of Cardiology. 2003 May 21;41(10):1707-12. PubMed PMID: 12767651. Epub 2003/05/28. eng.
30. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. The New England journal of medicine. 2005 Apr 14;352(15):1539-49. PubMed PMID: 15753115. Epub 2005/03/09. eng.
31. MEMBERS WC, Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation. Circulation. 2009 April 14, 2009;119(14):e391-e479.
32. Múnera AG, Restrepo G, Duque M, Cubides C, Uribe W, Medina E, et al. Terapia de resincronización cardiaca: experiencia, seguimiento clínico y ecocardiográfico, y optimización del dispositivo con ecocardiografía. Revista Colombiana de Cardiología. 2007;14(2):0120- 5633.
33. Garrigue S, Bordachar P, Reuter S, Jais P, Kobeissi A, Gaggini G, et al. Comparison of permanent left ventricular and biventricular pacing in patients with heart failure and chronic atrial fibrillation: prospective haemodynamic study. Heart (British Cardiac Society). 2002 Jun;87(6):529-34. PubMed PMID: 12010933. Pubmed Central PMCID: PMC1767120. Epub 2002/05/16. eng.
34. Leclercq C, Walker S, Linde C, Clementy J, Marshall AJ, Ritter P, et al. Comparative effects of permanent biventricular and right-univentricular pacing in heart failure patients with chronic atrial fibrillation. European heart journal. 2002 Nov;23(22):1780-7. PubMed PMID: 12419298. Epub 2002/11/07. eng.
35. Auricchio A, Stellbrink C, Sack S, Block M, Vogt Jü, Bakker P, et al. long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. Journal of the American College of Cardiology. 2002;39(12):2026-33.
36. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. The New England journal of medicine. 2004 May 20;350(21):2140-50. PubMed PMID: 15152059. Epub 2004/05/21. eng.
37. Linde C, Abraham WT, Gold MR, St John Sutton M, Ghio S, Daubert C. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms. Journal of the American College of Cardiology. 2008 Dec 2;52(23):1834-43. PubMed PMID: 19038680. Epub 2008/11/29. eng.
38. Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, et al. Cardiac-resynchronization therapy for mild-to-moderate heart failure. New England Journal of Medicine. 2010;363(25):2385-95
2. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. European heart journal. 2012;33(14):1787-847.
3. Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, et al. Heart Disease and Stroke Statistics—2009 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119(3):480-6.
4. Cowie MR, Mosterd A, Wood DA, Deckers JW, Poole-Wilson PA, Sutton GC, et al. The epidemiology of heart failure. European heart journal. 1997 Feb;18(2):208-25. PubMed PMID: 9043837.
5. DANE. Análisis de situación de salud según regiones Colombia. In: social Mdsyp, editor. 2013.
6. DANE. Estadísticas vitales 2013. Available from: http://www.dane.gov.co/index.php/poblacion- y-demografia/nacimientos- -defunciones.
7. Swedberg K, Cleland J, Dargie H, Drexler H, Follath F, Komajda M, et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005) The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. European heart journal. 2005;26(11):1115-40.
8. Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, Boriani G, Breithardt O-A, et al. 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy The Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA). European heart journal. 2013;34(29):2281-329.
9. Exner DV, Birnie DH, Moe G, Thibault B, Philippon F, Healey JS, et al. Canadian Cardiovascular Society Guidelines on the Use of Cardiac Resynchronization Therapy: Evidence and Patient Selection. Canadian Journal of Cardiology. 2013;29(2):182-95.
10. Keegan R, Vanegas D. Guías, Recomendaciones y Niveles de Evidencia Relacionados con La Estimulación Cardiaca y la Electrofisiología Cardiovascular 2011:26
11. Daubert JC, Saxon L, Adamson PB, Auricchio A, Berger RD, Beshai JF, et al. 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management. Heart Rhythm. 2012 Sep;9(9):1524-76. PubMed PMID: 22939223. Epub 2012/09/04. eng.
12. Hernández Madrid A, Escobar Cervantes C, Blanco Tirado B, Marín Marín I, Moya Mur JL, Moro C. Resincronización cardíaca en la insuficiencia cardíaca: bases, métodos, indicaciones y resultados. Revista Española de Cardiología. 2004;57(07):680-93.
13. Callejo D, Martín Cuerra M, Blasco JA. Terapia de resincronización cardiaca. Evaluación económica. Plan de calidad para el Sistema Nacional de Salud del Ministerio de Sanidad y Política Social. Informes de evaluación de Tecnología sanitaria UETS. Agencia Laín Entralgo, 2010.
14. 2008 Quality and Outcomes Abstracts. Circulation. 2008 May 27, 2008;117(21):e409-e68.
15. Mirowski M, Reid PR, Mower MM, Watkins L, Gott VL, Schauble JF, et al. Termination of malignant ventricular arrhythmias with an implanted automatic defibrillator in human beings. The New England journal of medicine. 1980 Aug 7;303(6):322-4. PubMed PMID: 6991948. Epub 1980/08/07. eng.
16. Linde C, Leclercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, et al. Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study. Journal of the American College of Cardiology. 2002 Jul 3;40(1):111-8. PubMed PMID: 12103264. Epub 2002/07/10. eng.
17. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization in chronic heart failure. New England Journal of Medicine. 2002;346(24):1845-53.
18. Lemos Júnior HPd, Atallah ÁN. Cardiac resynchronization therapy in patients with heart failure: systematic review. Sao Paulo Medical Journal. 2009;127(1):40-5.
19. Callejo D, Guerra M, Hernández-Madrid A, Blasco JA. Evaluación económica de la terapia de resincronización cardiaca. Revista española de cardiología. 2010;63(11):1235-43.
20. Coma Samartín R, Sancho-Tello de Carranza MJ, Ruiz Mateas F, Leal del Ojo González J, Fidalgo Andrés ML. Registro Español de Marcapasos. VIII Informe Oficial de la Sección de Estimulación Cardiaca de la Sociedad Española de Cardiología (2010). Revista Española de Cardiología. 2011;64(12):1154-67.
21. Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC, Committee ASA, et al. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database. Journal of the American College of Cardiology. 2006 Jan 3;47(1):76-84. PubMed PMID: 16386668.
22. Actualizacion del Plan Obligatorio de Salud en Colombia, 005121 (2013).
23. Wolpert C, Lubinski A, Bissinger A, Merkely B, Priori S, Brugada J. Barriers to implementation of evidence-based electrical therapies and the need for outcome research: role of European registries. Europace. 2011;13(suppl 2):ii18- ii20.
24. Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. JAMA : the journal of the American Medical Association. 2003 May 28;289(20):2685-94. PubMed PMID: 12771115. Epub 2003/05/29. eng.
25. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. The New England journal of medicine. 2004;350(21):2140-50.
26. Beshai JF, Grimm RA, Nagueh SF, Baker JH, Beau SL, Greenberg SM, et al. Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. New England Journal of Medicine. 2007;357(24):2461-71.
27. Ruschitzka F, Abraham WT, Singh JP, Bax JJ, Borer JS, Brugada J, et al. Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex. New England Journal of Medicine. 2013;369(15):1395-405. PubMed PMID: 23998714.
28. Bansch D, Antz M, Boczor S, Volkmer M, Tebbenjohanns J, Seidl K, et al. Primary prevention of sudden cardiac death in idiopathic dilated cardiomyopathy: the Cardiomyopathy Trial (CAT). Circulation. 2002 Mar 26;105(12):1453- 8. PubMed PMID: 11914254. Epub 2002/03/27. eng.
29. Strickberger SA, Hummel JD, Bartlett TG, Frumin HI, Schuger CD, Beau SL, et al. Amiodarone versus implantable cardioverter- defibrillator:randomized trial in patients with nonischemic dilated cardiomyopathy and asymptomatic nonsustained ventricular tachycardia--AMIOVIRT. Journal of the American College of Cardiology. 2003 May 21;41(10):1707-12. PubMed PMID: 12767651. Epub 2003/05/28. eng.
30. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. The New England journal of medicine. 2005 Apr 14;352(15):1539-49. PubMed PMID: 15753115. Epub 2005/03/09. eng.
31. MEMBERS WC, Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/ American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation. Circulation. 2009 April 14, 2009;119(14):e391-e479.
32. Múnera AG, Restrepo G, Duque M, Cubides C, Uribe W, Medina E, et al. Terapia de resincronización cardiaca: experiencia, seguimiento clínico y ecocardiográfico, y optimización del dispositivo con ecocardiografía. Revista Colombiana de Cardiología. 2007;14(2):0120- 5633.
33. Garrigue S, Bordachar P, Reuter S, Jais P, Kobeissi A, Gaggini G, et al. Comparison of permanent left ventricular and biventricular pacing in patients with heart failure and chronic atrial fibrillation: prospective haemodynamic study. Heart (British Cardiac Society). 2002 Jun;87(6):529-34. PubMed PMID: 12010933. Pubmed Central PMCID: PMC1767120. Epub 2002/05/16. eng.
34. Leclercq C, Walker S, Linde C, Clementy J, Marshall AJ, Ritter P, et al. Comparative effects of permanent biventricular and right-univentricular pacing in heart failure patients with chronic atrial fibrillation. European heart journal. 2002 Nov;23(22):1780-7. PubMed PMID: 12419298. Epub 2002/11/07. eng.
35. Auricchio A, Stellbrink C, Sack S, Block M, Vogt Jü, Bakker P, et al. long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. Journal of the American College of Cardiology. 2002;39(12):2026-33.
36. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. The New England journal of medicine. 2004 May 20;350(21):2140-50. PubMed PMID: 15152059. Epub 2004/05/21. eng.
37. Linde C, Abraham WT, Gold MR, St John Sutton M, Ghio S, Daubert C. Randomized trial of cardiac resynchronization in mildly symptomatic heart failure patients and in asymptomatic patients with left ventricular dysfunction and previous heart failure symptoms. Journal of the American College of Cardiology. 2008 Dec 2;52(23):1834-43. PubMed PMID: 19038680. Epub 2008/11/29. eng.
38. Tang AS, Wells GA, Talajic M, Arnold MO, Sheldon R, Connolly S, et al. Cardiac-resynchronization therapy for mild-to-moderate heart failure. New England Journal of Medicine. 2010;363(25):2385-95
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